ESMO-MCBS v1.1: statistical and patient-relevant shortcomings
نویسندگان
چکیده
منابع مشابه
Detailed statistical assessment of the characteristics of the ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS) threshold rules
BACKGROUND The European Society for Medical Oncology (ESMO) has developed the ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS), a tool to assess the magnitude of clinical benefit from new cancer therapies. Grading is guided by a dual rule comparing the relative benefit (RB) and the absolute benefit (AB) achieved by the therapy to prespecified threshold values. The ESMO-MCBS v1.0 dual rule e...
متن کاملUtilisation of the ESMO-MCBS in practice of HTA.
1Ludwig Boltzmann Institute of Health technology Assessment, Vienna), Austria; 2Independent Pharmaceutical Consultant, Mellieha, Malta; 3Department of Finance, University of Austria, Vienna, Austria; 4Medicinal Products Department, Health Insurance Institute of Slovenia, Ljubljana, Slovenia; 5Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow,UK; 6Depa...
متن کاملESMO-Magnitude of Clinical Benefit Scale version 1.1.
Background The ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS) version 1.0 (v1.0) was published in May 2015 and was the first version of a validated and reproducible tool to assess the magnitude of clinical benefit from new cancer therapies. The ESMO-MCBS was designed to be a dynamic tool with planned revisions and updates based upon recognition of expanding needs and shortcomings identifi...
متن کاملESMO - Magnitude of Clinical Benefit Scale V.1.0 questions and answers
The ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS) is a standardised, generic, validated tool to stratify the magnitude of clinical benefit that can be anticipated from anticancer therapies. The ESMO-MCBS is intended to both assist oncologists in explaining the likely benefits of a particular treatment to their patients as well as to aid public health decision makers' prioritise therapies...
متن کاملThe European Society for Medical Oncology 'Magnitude of Clinical Benefit Scale' field-tested in infrequent tumour entities: an extended analysis of its feasibility at the Medical University of Vienna
BACKGROUND The European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS) is a new tool to quantify the clinical benefit that may be anticipated from a novel anticancer treatment. We present here an analysis on the feasibility of the ESMO-MCBS in less frequent tumour entities. METHODS This study evaluates the practicability of the ESMO-MCBS for metastatic neuroendoc...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2018
ISSN: 0923-7534
DOI: 10.1093/annonc/mdy026